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Open Access Articles- Top Results for VDAC2

VDAC2

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Identifiers
SymbolsVDAC2 ; POR
External IDsOMIM193245 MGI106915 HomoloGene37765 ChEMBL: 6190 GeneCards: VDAC2 Gene
Orthologs
SpeciesHumanMouse
Entrez741722334
EnsemblENSG00000165637ENSMUSG00000021771
UniProtP45880Q60930
RefSeq (mRNA)NM_001184783NM_011695
RefSeq (protein)NP_001171712NP_035825
Location (UCSC)Chr 10:
76.97 – 76.99 Mb
Chr 14:
21.83 – 21.85 Mb
PubMed search[1][2]

Voltage-dependent anion-selective channel protein 2 is a protein that in humans is encoded by the VDAC2 gene.[1][2] The protein encoded by this gene is a voltage-dependent anion channel.[1][2]

VDAC2 is involved in the regulation of mitochondrial apoptosis.[3]

References

  1. 1.0 1.1 Blachly-Dyson E, Baldini A, Litt M, McCabe ER, Forte M (Jul 1994). "Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms". Genomics 20 (1): 62–7. PMID 7517385. doi:10.1006/geno.1994.1127. 
  2. 2.0 2.1 Messina A, Oliva M, Rosato C, Huizing M, Ruitenbeek W, van den Heuvel LP, Forte M, Rocchi M, De Pinto V (Apr 1999). "Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered". Biochem Biophys Res Commun 255 (3): 707–10. PMID 10049775. doi:10.1006/bbrc.1998.0136. 
  3. Cheng EH, Sheiko TV, Fisher JK, Craigen WJ, Korsmeyer SJ (July 2003). "VDAC2 inhibits BAK activation and mitochondrial apoptosis". Science 301 (5632): 513–7. PMID 12881569. doi:10.1126/science.1083995. 

Further reading

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External links


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