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Vindesine

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Vindesine
File:Vindesin.svg
Systematic (IUPAC) name
methyl (5S,7S,9S)- 9-[(2β,3β,4β,5α,12β,19α)- 3-(aminocarbonyl)- 3,4-dihydroxy- 16-methoxy- 1-methyl- 6,7-didehydroaspidospermidin- 15-yl]- 5-ethyl- 5-hydroxy- 1,4,5,6,7,8,9,10-octahydro- 2H- 3,7-methanoazacycloundecino[5,4-b]indole- 9-carboxylate
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
  • AU: D
  • (Prescription only)
Intravenous
Pharmacokinetic data
Protein binding 65-75%
Metabolism Hepatic (CYP3A4-mediated)
Half-life 24 hours
Excretion Biliary and renal
Identifiers
59917-39-4 7pxY
L01CA03
PubChem CID 40839
DrugBank DB00309 7pxY
ChemSpider 37302 7pxY
UNII RSA8KO39WH 7pxY
KEGG D01769 7pxY
ChEBI CHEBI:36373 7pxY
ChEMBL CHEMBL219146 7pxY
Chemical data
Formula C43H55N5O7
753.926 g/mol
 14pxY (what is this?)  (verify)

Vindesine is an anti-mitotic vinca alkaloid used in chemotherapy. It is used to treat many different types of cancer, including leukaemia, lymphoma, melanoma, breast cancer, and lung cancer.[1]

References

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