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Volutin granules

Volutin granules are an intracytoplasmic (inside the cytoplasm of a cell) storage form of complexed inorganic polyphosphate,[1] the production of which is used as one of the identifying criteria when attempting to isolate Corynebacterium diphtheriae on Löffler's medium. Polyphosphate granules are called metachromatic granules due to their displaying the metachromatic effect; they appear red when stained with methylene blue.[2]


  1. ^ Reddy Pallerla, Srinivas; Knebel, Sandra; Polen, Tino; Klauth, Peter; Hollender, Juliane; Wendisch, Volker F; Schoberth, Siegfried M (2005). "Formation of volutin granules in Corynebacterium glutamicum". FEMS Microbiology Letters (Institut fr Biotechnologie (IBT-1), Forschungszentrum Jlich, D-52425 Jlich, Germany; Institut fr Chemie und Dynamik der Geosphre (ICG-IV: Agrosphre), Forschungszentrum Jlich, D-52425 Jlich, Germany; Institut fr Hygiene und Umweltmedizin, Universittsklinikum, RWTH-Aachen, D-52074 Aachen, Germany) 243 (1): 133–140. PMID 15668011. doi:10.1016/j.femsle.2004.11.047. 
  2. ^ Willey, J. M., Sherwood, L. M. and Woolverton, C. J. (2011). Prescott's Microbiology, 8th Ed. McGraw Hill.