Open Access Articles- Top Results for WAY-213,613


Systematic (IUPAC) name
(2S)-2-amino-4-[4-(2-bromo-4,5-difluorophenoxy)anilino]-4-oxobutanoic acid
Clinical data
868359-05-1 7pxY
PubChem CID 11531745
ChemSpider 9706528 7pxN
ChEMBL CHEMBL1628669 7pxN
Chemical data
Formula C16H13BrF2N2O4
415.186 g/mol
 14pxN (what is this?)  (verify)

WAY-213,613 is a drug which acts as a reuptake inhibitor for the glutamate transporter subtype EAAT2, selective over other glutamate transporter subtypes and highly selective over metabotropic and ionotropic glutamate receptors.[1] It is used in scientific research into the function of the glutamate transporters.[2]


  1. Dunlop, J; McIlvain, HB; Carrick, TA; Jow, B; Lu, Q; Kowal, D; Lin, S; Greenfield, A et al. (2005). "Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2". Molecular Pharmacology 68 (4): 974–82. PMID 16014807. doi:10.1124/mol.105.012005. 
  2. Karatas-Wulf, U; Koepsell, H; Bergert, M; Sönnekes, S; Kugler, P (2009). "Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells". Neuroscience 161 (3): 794–805. PMID 19364521. doi:10.1016/j.neuroscience.2009.04.017. 

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