Open Access Articles- Top Results for ZNF638


SymbolsZNF638 ; NP220; ZFML; Zfp638
External IDsOMIM614349 MGI1203484 HomoloGene7447 GeneCards: ZNF638 Gene
RNA expression pattern
File:PBB GE ZNF638 213775 x at tn.png
File:PBB GE ZNF638 211257 x at tn.png
More reference expression data
RefSeq (mRNA)NM_001014972NM_001166371
RefSeq (protein)NP_001014972NP_001159843
Location (UCSC)Chr 2:
71.5 – 71.66 Mb
Chr 6:
83.91 – 83.99 Mb
PubMed search[1][2]

Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.[1][2]

The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.[2]


ZNF638 has been shown to interact with FHL2.[3]


  1. ^ Inagaki H, Matsushima Y, Nakamura K, Ohshima M, Kadowaki T, Kitagawa Y (Jul 1996). "A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain". J Biol Chem 271 (21): 12525–31. PMID 8647861. doi:10.1074/jbc.271.21.12525. 
  2. ^ a b "Entrez Gene: ZNF638 zinc finger protein 638". 
  3. ^ Ng, Enders Kai On; Chan Kwok Keung; Wong Chi Hang; Tsui Stephen Kwok Wing; Ngai Sai Ming; Lee Simon Ming Yuen; Kotaka Masayo; Lee Cheuk Yu; Waye Mary Miu Yee; Fung Kwok Pui (2002). "Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220". J. Cell. Biochem. (United States) 84 (3): 556–66. ISSN 0730-2312. PMID 11813260. doi:10.1002/jcb.10041. 

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